Appearances Honda CBR250R, hardly much different from the usual motor sport (sport touring), such as Honda or Yamaha Tiger Bison, only diusungnya machine large enough, ie 250 CC with a single-cylinder DOHC, 6-speed, 4-valve, refrigerated liquid (liquid cooled), and of course dump gas emissions in compliance with Euro-2 standard. So, do not compare well with motor sport Kawasaki Ninja 250, which looks more 'fierce' and really like motor racing.

Honda CBR250R comes with the latest generation of design concepts to full-fairing sport category, its design based on "Mass Centralization Form". Model Honda CBR250R is also inspired from a combination of models and VFR1200F Honda CBR1000RR.